Conversion of HBV serological marker carriers and its influential factors
Liu, T.P.
Zhonghua Liu Xing Bing Xue Za Zhi 9(5): 274-277
1988
ISSN/ISBN: 0254-6450 PMID: 3228854 Document Number: 318997
485 HBV serological marker carriers were followed up for three years. The three years negative conversion rate of both HBsAg and Anti-HBc in carriers was 40.27%. Four markers negative conversion rate of HBsAg, Anti-HBc,HBeAg and Anti-HBe was 30.62% after three years observation. Positive in Anti-HBs is helpful for negative conversion, ratio of negative conversion rates between Anti-HBc positive and negative is 1.32. But the effect of Anti-HBs was modified by Anti-HBc carriage. Negative conversion rate of Anti-HBc carriers was lower, and the higher the Anti-HBc titer, the lower the rate of negative conversion. Educational level and age were negatively correlated with conversion.