Glycated albumin level and its influential factors in type 2 diabetes mellitus
Li, Q.; Wu, S.-H.; Pan, J.-M.; Tang, J.-L.; Zhang, Y.; Lu, H.-J.; Bao, Y.-Q.; Jia, W.-P.; Xiang, K.-S.
Zhonghua Yi Xue Za Zhi 87(42): 2994-2996
2007
ISSN/ISBN: 0376-2491 PMID: 18261334 Document Number: 611168
To provide evidence for assessing glycated albumin (GA) appropriately cliniccally through determining the GA level of type 2 diabetes mellitus (DM) patients and analyzing its influential factors. Continuous glucose monitor system was used to monitor the levels of fasting plasmic glucose (FPG), 2-hour post-prandial plasmic glucose (2hPG), GA, and glycated hemoglobin (HbA1c) in 445 type 2 DM in-patients. (1) The mean GA value was 24.9% +/- 7.0% and the mean HbA1c was 8.9% +/- 2.2%. (2) GA value was associated with HbA1c (P < 0.001). GA was positively correlated with FPG, 2hPG, and mean blood glucose (MBG) (all P < 0.01). (3) GA value was negatively correlated with BMI (P < 0.01). (4) Multiple stepwise regression analysis showed that HbA1c, BMI, and FPG were the main influential factors of GA. (1) GA value has good relationship with HbA1c, a golden standard to reflect the glycemic control in a long period. (2) BMI should be concerned when assessing GA value of DM patients, especially of the obese and thin subjects.