Localized scleroderma in childhood
Domenici, R.; Simoni, F.; Camici, G.
La Pediatria Medica e Chirurgica Medical and Surgical Pediatrics 10(3): 297-302
1988
ISSN/ISBN: 0391-5387 PMID: 3186514 Document Number: 318718
Scleroderma is a rare disease in children: the clinical presentation in childhood is even more varied than in adult life. It is characterized by 'hard skin' with cutaneous features including hypo- and hyperpigmentation, thickening or thinning and loss of elasticity. It ranges from circumscribed and self-limiting pigmentary disorders to disabling and disfiguring involvement of an extremity and a rapidly fatal outcome. Scleroderma must be differentiated from many scleroderma-like conditions. Therapeutic problems are also discussed.