Relationship between intrauterine device and intrauterine pressure and levels of PGs in uterine fluid
Yang, Q.; Tian, X.K.; Chau, X.J.
Sheng Zhi Yu Bi Yun 11(4): 39-45
1991
ISSN/ISBN: 0253-357X PMID: 12284921 Document Number: 317509
73 healthy, parous nonpregnant women were examined for intrauterine pressure (IUP) and levels of 6-keto-prostaglandin Flalpha (PGF1alpha) and TXB2 in uterine fluid were examined before and after insertion of an IUD and then 1 month after insertion. The authors wanted to see the relationship between IUP, IUD expulsion, and relative factors affecting IUP. Results were as follows: 1. The IUP of healthy parous women during days 8-14 of the menstrual cycle was 1.91 +or- 1.18 kPa (95% confidence limits: 1.64, 2.18 kPa) and frequency was 2.68 +or- 1.25 times/minute. 2. In spite of IUD insertion, IUP rose significantly. But IUD insertion did not produce any longterm effects of IUP (p0.05). IUP had some effects on IUD expulsion. Prior to IUD insertion, the higher the IUP was, the easier was the IUD expulsion (p0.05). 3. Disparity in laxity degree of internal cervical orifice and gravida/parity had no effects on IUP (p,0.05). Insertion of different types of IUD had no effects on IUP either (p0.01). 4. 1 month after IUD use, the levels of 6-keto-PGF1alpha and TXB2 in uterine fluid could rise significantly, but the rate of P/T had not remarkable changes. The results indicate that a linear negative correlation exists between IUP and ratio of P/T (r=0/264, p0.05). (Author's modified)