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Quantitative analysis of aldosterone's role in potassium regulation

Young, D.B.

American Journal of Physiology 255(5 Pt 2): F811-F822

1988

ISSN/ISBN: 0002-9513
PMID: 3056039
Document Number: 317447
Aldosterone is part of a complex system that regulates plasma potassium concentration by affecting the renal excretion of the ion as well as its distribution within the body. Because there are other components of the system, it has been difficult to determine the physiological significance of aldosterone in K regulation by attempting to study the hormone's effects in isolation. A quantitative analysis of the K control system is used to provide information concerning the physiological role of aldosterone in K regulation in normal and pathological conditions, as well as during pharmacological interventions.

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