Aldosterone, sodium and potassium concentrations in the blood of patients with myocardial infarction after acute hydrocortisone load
Iakobson, M.G.; Kuimov, A.D.; Sorokin, A.S.; Gizatulin, Z.I.
Kardiologiia 23(9): 62-65
1983
ISSN/ISBN: 0022-9040 PMID: 6645193 Document Number: 212983
Patients with acute myocardial infarction were repeatedly investigated in the course of their disease. Blood aldosterone was assayed radioimmunologically to determine its baseline level and response to the acute hydrocortisone load test. Cases where acute myocardial infarction was combined with essential hypertension were characterized by high blood aldosterone baseline, as were cases with circulatory insufficiency developing at the acute stage of infarction. Pattern of aldosterone variation in response to hydrocortisone administration was dependent on the phase of infarction and provided indirect evidence of glucocorticoid activity at various dates of the disease. The acute stage was associated with hyperaldosteronemia.