Flow cytometry in analysis of precancerous lesions of the esophagus
Hou, J.; Zuo, L.F.; Liu, H.X.; Li, S.S.; Lin, Y.Z.; Wang, D.Z.; Guo, J.W.
Zhonghua Zhong Liu Za Zhi 10(2): 105-108
1988
ISSN/ISBN: 0253-3766 PMID: 3208646 Document Number: 315665
DNA content of the severe dysplasia cells in the esophageal epithelial was quantitatively analysed using flow cytometry and compared with those of the normal, mild dysplasia and cancer cells. The results showed that DNA index of the severe dysplasia cells was 1.27 .+-. 0.11 and there was a significant difference between its value and those of the normal (1.0 .+-. 0l.02), mild dysplasia (1.01 .+-. 0.03) and cancer cells (1.73 .+-. 0.35). The DNA content of severe dysplasia cells lies between the normal and cancer cells. The hyperplasia degree of the severe dysplasia cells parallels their DNA contents. This study indicates that flow ccytometry is a useful supplementary tool for diagnosis of the tumor.