A karyometric study of the supraoptic and paraventricular nuclei of the hypothalamus of kainic acid-treated mice
Srebro, Z.; Lach, H.; Plackowska, M.
Folia Biologica 36(1-2): 53-58
1988
ISSN/ISBN: 0015-5497 PMID: 3169308 Document Number: 314715
Kainic acid administered in a daily dose of 12.mu.g/g body weight for 7 consecutive days caused a statistically significant decrease in nuclear volume in neurons of the supraoptic and paraventricular nuclei of the hypothalamus. This fall was evident both in young (28-day-old) and mature (120-day-old) animals. The changes were greater in the young animals and in males.
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