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Effect of intraoperative local polyvinylpyrrolidone iodine administration on the risk of wound infection following appendectomy

Eggert, A.; Baumann, M.

Zentralblatt für Chirurgie 113(6): 391-396

1988

ISSN/ISBN: 0044-409X
PMID: 3389001
Document Number: 313733
A study conducted into 91 appendectomised patients revealed wound infection rates to worsen from eight to 26 per cent (p less than 0.05) in the wake of locally delimited intra-operative application of povidone-iodine solution, two per cent in concentration. No other factors were found to be responsible for that aggravation. Tissue toxicity was found to outweight bactericidal effects, even with application in diluted and PVP-bonded form. Hence, povidone-iodine solutions not even in diluted form should ever be applied to wound treatment.

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