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Electron microscopic immunohistochemistry in the diagnosis of human lymphotropic viral diseases

Timár, J.; Smirnova, E.A.; Lapis, K.

Voprosy Onkologii 34(12): 1439-1442

1988

ISSN/ISBN: 0507-3758
PMID: 2905847
Document Number: 312575
Immunohistochemistry is finding an ever increasing application for electron microscopic diagnosis of human viral diseases. Certain progress has been made in the use of peroxidase-DAB/OsO4 as an electron-dense marker, and colloid gold. The paper discusses immunohistochemistry application for electron microscopic detection of such lymphotropic viruses as VSV (virus of vesicular stomatitis cultured in mink's lung cells), HTLV-1 (virus of human T4-cell C91P1 lymphoma culture) and HTLV-III/HIV-1 (virus growing in human T4-cell H9 culture).

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