Myxedematous coma. Prognostic and therapeutic re-evaluation
Fenichel, P.; Zartarian, M.; Grimaud, D.; Brucker, F.; Morand, P.; Harter, M.; Fredenrich, A.; Zartariana, M.; Frimaud, D.
Presse Medicale 17(26): 1345-1348
1988
ISSN/ISBN: 0755-4982 PMID: 2970079 Document Number: 310873
The prognostic factors and therapeutic approaches in myxoedema coma--a rare but serious medical emergency--were re-evaluated from a retrospective study of 10 cases. The immediate respiratory risk can be prevented by referring these patients immediately to an intensive care unit. The patient's cardiovascular status before and after coma determines the prognosis for life and serves as guideline to treatment. Hormone replacement therapy with initial injection of a loading dose of thyroxine seems to improve the prognosis by ensuring rapid recovery of the principal vital functions.