Actin interaction with the plasma membrane fraction of cells of murine fibroblast L sublines differing by growth type in culture

Pershina, V.P.; Pinaev, G.P.; Semenova, E.G.

Tsitologiia 30(5): 582-588

1988


ISSN/ISBN: 0041-3771
PMID: 2845616
Document Number: 310301
The association between murine fibroblast L plasma membranes and actin was studied by means of low-shear viscometry of membrane-actin mixtures. Membrane fractions of 3 genetically related sublines of L cells were used differing in cytoskeleton structural organization. The suspension cell subline LS membranes showed actin gelatin activity. On the contrary, the membranes of monolayer cell sublines L-929 and LSM were seen to bind actin and to cause decrease in viscosity. Possible mechanisms of such interactions are discussed.

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