Suppressor T cell function in undifferentiated collagenoses
Becker, H.; Würden, E.; Helmke, K.
Zeitschrift für Rheumatologie 47(3): 143-145
1988
ISSN/ISBN: 0340-1855 PMID: 2975106 Document Number: 310102
In order to study early cellular defects in connective tissue diseases, suppressor T-cell function in undifferentiated connective tissue syndromes was determined. The capacity of T8(CD8)-positive cells to suppress pokeweed mitogen-induced IgG and IgM secretion was studied in 14 patients. Compared with normals, a reduced activity of cells to suppress the IgM response was shown, whereas the suppression of IgG secretion was not affected.
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