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The analgesic effect of various fractions of the supernatant of a bone marrow cell culture in pathologic pain

Grafova, V.N.; Danilova, E.I.; Zakharova, L.A.; Mikhaĭlova, A.A.

Biulleten' Eksperimental'noi Biologii i Meditsiny 106(12): 653-655

1988

ISSN/ISBN: 0365-9615
PMID: 3207866
Document Number: 309549
Different fractions of bone marrow cell culture supernatant effects on pathological pain have been studied. It is shown that all studied fractions have analgesic effect and inhibit strong pain syndrome induced by generator of pathologically enhanced excitation. In distinction from commercial drug myelopid bone marrow supernatant fractions with high and low molecular weight exert analgesic effect in low concentrations not having muscle-relaxant and narcotic influence. It suggests the possibility of creation of some new highly effective analgesic drugs to abolish pain syndromes.

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Florensa, L.; Woessner, S.; Lafuente, R.; Vilá, R.M.; Almarcha, J.; Marill, M.R.; Sans-Sabrafen, J. 1985: In vitro culture of the pluripotent stem cell of human bone marrow (CFU-GEMML). Technical, morphological, conventional and cytochemical aspects Sangre 30(3): 292-301
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