Immunomodulating action of a preparation of yeast dsRNA on cellular immunity in mice
Fadina, V.A.; Razvorotnev, V.A.
Antibiotiki i Khimioterapiia 33(7): 527-529
1988
ISSN/ISBN: 0235-2990 PMID: 2973289 Document Number: 308049
The effect of a dsRNA preparation (an interferon inductor) on DTH induced by SRBC was studied. It was shown that at optimal antigenic load the dsRNA preparation inhibited DTH whereas at suboptimal and supraoptimal loads the preparation stimulated it. The findings indicated that the dsRNA preparation had an immunoregulatory effect. The immunoregulatory properties of the preparation must be associated with its action on the lymphocyte suppressor cells and macrophages.