Circadian rhythm in myocardial infarct
Enciso, R.; Ramos, M.A.; Badui, E.; Hurtado, R.
Archivos del Instituto de Cardiologia de Mexico 58(2): 159-162
1988
ISSN/ISBN: 0020-3785 PMID: 2899997 Document Number: 307248
In order to determine if the beginning of the Myocardial Infarction (MI) is at random along the day or if it follows a circadian rhythm, we analyzed the clinical charts of 819 patients admitted to the Coronary Care Unite. Among them, 645 were male and 174 female. It was established that the beginning of the MI follows a circadian rhythm with maximal frequency between 8 and 9 a.m. and minimal at 0 hours (p greater than 0.01). This rhythm is sex independent. In patients younger than 45 years as well as those who received beta-block agents in less than 24 hours previous the MI no circadian rhythm was observed.