Responses of the retinal pigment epithelium of the mouse after acute loss of blood
Li, W.W.; Yew, D.T.
Acta Anatomica 133(4): 337-340
1988
ISSN/ISBN: 0001-5180 PMID: 3227795 Document Number: 306996
Albino mice were bled through the hearts by cardiac puncture and 1/2, 1/3 and 1/4 mls of blood were taken out from 3 groups of animals, respectively. Half of the experimental animals were reinfused with 5% dextrose 1 h after bleeding. All were killed either 2, 5, 9, 24, 48 and 72 h after bleeding, and the phagosome numbers per 5 pigment cells counted and compared with control retinae. A severe decrease was evident after bleeding and the decrease leveled off 48 hg afterwards. Reinfusion with dextrose had a positive beneficial effect.