Comparison of sensitivity of Mycobacterium spp. to combinations of clavulanic acid & penicillins with certain antitubercular agents
Bhattacharya, C.P.; Charkrabarty, A.N.; Dastidar, S.G.
Indian Journal of Medical Research 88: 118-123
1988
ISSN/ISBN: 0019-5340 PMID: 3198169 Document Number: 306989
The sensitivity to augmentin of several reference strains of mycobacteria was assessed by colony reduction and disc-diffusion techniques on the Lowenstein-Jensen medium as well as by the tube-dilution technique using the Kirchner's liquid medium. With the exceptions of Mycobacterium smegmatis and M. skinsnes, the other mycobacteria, including M. tuberculosis (H37Rv,H37Ra) showed remarkable sensitivity to augmentin; further, this drug in combination with other antitubercular drugs (INH, ethambutol, rifampicin and streptomycin) exhibited synergistic and powerful inhibitory effects.