Clinical evaluation of sulbactam + ampicillin in the treatment of pediatric urinary tract infections
Solbiati, M.; Danzi, M.C.; D'Orazio, C.; Bassetti, D.
Chemioterapia International Journal of the Mediterranean Society of ChemoTherapy 7(6): 393-395
1988
ISSN/ISBN: 0392-906X PMID: 3219751 Document Number: 306946
Twenty-five children (16 females and 9 males) aged from 8 months to 10 years with clinical and laboratory evidence of UTI were treated with sulbactam + ampicillin (SBT/AMP). Twenty-four of them were suffering from cystitis and one from pyelonephritis. Four of them were treated unsuccessfully prior to entry in the trial. The mean final dose of SBT/AMP was 47.69 mg/kg/die (ratio of SBT-AMP was 1:2). The patients were treated for 3 to 8 days (mean: 4.76 days). 84% were treated by i.m. route. No side effects or adverse experience were reported. Clinical cure was achieved in 25 patients (100%).