Phenotypes of resistance to antibiotics of Acinetobacter baumannii. Impact on therapeutic orientation

Ygout, J.F.; Pasteau, C.; Mugnier, P.; Berlioux, J.; Daguet, G.L.; Ygout, J.F; Pasteau, C; Mugnier, P; Berlioux, J; Daguet, G.L

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Phenotypes of resistance to antibiotics of Acinetobacter baumannii. Impact on therapeutic orientation

Ygout, J.F.; Pasteau, C.; Mugnier, P.; Berlioux, J.; Daguet, G.L.

Pathologie-Biologie 36(3): 245-249

1988

ISSN/ISBN: 0369-8114

PMID: 3283688

Document Number: 306344

By studying the sensitivity to antibiotics of 74 Acinetobacter baumannii strains, four phenotype groups were distinguished. The resistance of one of them (11% of the strains) to imipenem, argues against the therapeutic attitudes that now prevail. From studies on the kinetics of bactericidal activity of antibiotics and there association we propose what should be done in the laboratory to provide help to the physician for the antibiotic choice.