Role of the reticuloendothelial system in the pathogenesis of organ damage
Doran, J.E.; Lundsgaard-Hansen, P.
British Journal of Hospital Medicine 39(3): 221-225
1988
ISSN/ISBN: 0007-1064 PMID: 3282588 Document Number: 306191
Macrophages ingest foreign materials, effete and damaged tissues, and bacterial products. They also secrete biologically active products which promote and regulate host inflammatory responses. The balance between these macrophage activities may lead to the development of an effective and self-limiting inflammatory response or one that results in tissue damage and potentially in organ failure.