Animal experiment studies of morphologic changes in the trachea and lung in high frequency ventilation

Eckert, H.; Danzmann, E.; Voigt, H.; Oddoy, A.; Merker, G.; Harzendorf, E.; Bomm, M.; Noack, K.; Ritzau, E.

Zeitschrift für Erkrankungen der Atmungsorgane 170(2): 172-178

1988


ISSN/ISBN: 0303-657X
PMID: 3400290
Document Number: 306088
Prolonged high frequency ventilation (24 hrs) in dogs leads to morphological changes in the trachea as well as in the bronchi. Erosive changes of tracheal epithelium were observed whereas small bronchi and bronchioli exhibited luminal obstructions by mucus plugs, caused by hypersecretion of goblet cells. Using histochemical methods degenerative changes of bronchiolar epithelium were observed.

Document emailed within 1 workday
Secure & encrypted payments