Risk assessment of preeclampsia in advanced maternal age by uterine arteries Doppler at 17-21 weeks of gestation
Sritippayawan, S.; Phupong, V.
Journal of the Medical Association of Thailand 90(7): 1281-1286
2007
ISSN/ISBN: 0125-2208 PMID: 17710965 Document Number: 3059
Objective: To assess the risk of preeclampsia development in elderly gravidaruin by uterine arteries Doppler at 17-21 weeks' gestation.Material and Method. Pulsatility index (PI) of the uterine arteries was measured by color Doppler transabdominal sonography in 298 elderly gravida women at 17 - 21 weeks of gestation. The criterion for abnormal results was PI > 95(th) percentile of each gestational age and / or the presence of bilateral notches. The major end point was preeclampsia.Results: Ten woman (3.4%) developed preeclampsia. Two hundred and eighty-four women (95.3 %) had a normal Doppler flow of uterine arteries (P] 951 percentile of each gestational age), and 14 woman (4.7%) had abnormal Doppler flow of uterine arteries. The sensitivity, specificity, and positive and negative predictive values for detecting preeclampsia were 20%, 95.8%, 14.3%, and 97.2%, respectively.Conclusion: Women with mean PI > 95" of each gestational age have a high risk of developing preeclampsia. With the high negative predictive value, this test may be useful to minimize unnecessary interventions.
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