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Salivary kallikrein in Sjögren's syndrome

Friberg, B.; Jonsson, R.; Linde, A.

Clinical and Experimental Rheumatology 6(2): 135-138

1988

ISSN/ISBN: 0392-856X
PMID: 3180538
Document Number: 305805
Using a chromogenic substrate (H-D-Val-Leu-Arg-pNA) salivary kallikrein levels were measured in whole saliva samples from patients suffering from Sjögren's syndrome (SS). Compared to healthy control individuals, SS patients, especially those without corticosteroid medication, exhibited significantly elevated kallikrein levels. A diurnal variation was found with the highest kallikrein activities in morning saliva. No correlation between kallikrein levels and extension of the inflammation in labial salivary glands (focus score), salivary flow rates or diagnosis (primary versus secondary SS) could be observed. A pathogenic mechanism for kallikrein in autoimmune sialadenitis is discussed.

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Chisholm, D.M.; Mason, D.K. 1973: Salivary gland function in Sjögren's syndrome: a review British Dental Journal 135(9): 393-399
Fiessinger, J.N.; Jarnet, J.; Capron, L.; Housset, E. 1982: Systemic scleroderma : salivary immunoglobulins and the Gougerot-Sjögren syndrome Biomedicine and PharmacoTherapy 36(1): 51-54
Kemker, B.J.; Dayal, V.S.; DeMay, R.M. 1998: Sjögren's syndrome presenting with a minor salivary gland mass Journal of Otolaryngology 27(5): 298-300
Takaya, M.; Ichikawa, Y.; Koriyama, K.; Shimizu, H.; Arimori, S. 1984: Immunohistological studies on T lymphocyte subsets of the salivary glands in Sjögren's syndrome Ryumachi 24(4): 250-255
Hua, H.; Yu, S.; Xu, Z. 1995: An immunohistochemical study of HLA-DR expression in salivary glands from patients with Sjogren's syndrome Zhonghua Kou Qiang Yi Xue Za Zhi 30(3): 155-157; 192
Lindahl, G.; Hedfors, E.; Klareskog, L.; Forsum, U. 1985: Epithelial HLA-DR expression and T lymphocyte subsets in salivary glands in Sjögren's syndrome Clinical and Experimental Immunology 61(3): 475-482
Hammenfors, D.S.; Brun, J.G.; Jonsson, R.; Jonsson, M.V. 2015: Diagnostic utility of major salivary gland ultrasonography in primary Sjögren's syndrome Clinical and Experimental Rheumatology 33(1): 56-62
Markusse, H.M.; Pillay, M.; Breedveld, F.C. 1993: The diagnostic value of salivary gland scintigraphy in patients suspected of primary Sjögren's syndrome British Journal of Rheumatology 32(3): 231-235
Zhang, W.-Q.; Gong, X.; Xiong, P. 2018: The value of ultrasonic elastography in diagnosis of salivary gland lesions in patients with Sjogren's syndrome Shanghai Kou Qiang Yi Xue 27(1): 73-78
Decuzzi, M.; Tatulli, F.; Giampaolo, M.; Tesse, R.; Gasparre, M.; Pepe, G.; Decuzzi, P.; Asteriadis, I. 2006: Sialocintigraphy versus ultrasonography of the salivary glands in patients first diagnosed with Sjögren's syndrome Hellenic Journal of Nuclear Medicine 9(2): 103-105
Chehata, S.; Laatiri, M.A.; Bouaouina, N.; Bouzouita, K.; Slimane, K.; Mokni, M.; Korbi, S.; Bouzouita, H.; Ennabli, S. 2000: Gougerot-Sjögren syndrome disclosed by MALT lymphoma of the salivary glands. Report of 3 cases Annales de Medecine Interne 151(2): 93-96
Koski, H.; Janin, A.; Humphreys-Beher, M.G.; Sorsa, T.; Malmström, M.; Konttinen, Y.T. 2001: Tumor necrosis factor-alpha and receptors for it in labial salivary glands in Sjögren's syndrome Clinical and Experimental Rheumatology 19(2): 131-137
Li, H.-b.; Zhang, F.-c.; Zhang, X.; Gan, X.-d.; Shi, Y.-p.; Bai, Y.-n.; Tang, F.-l. 2010: Expression of SSA antigen epitopes in minor salivary glands from patients with primary Sjögren's syndrome Zhonghua Yi Xue Za Zhi 90(17): 1187-1191
Atkinson, J.C.; Travis, W.D.; Pillemer, S.R.; Bermudez, D.; Wolff, A.; Fox, P.C. 1990: Major salivary gland function in primary Sjögren's syndrome and its relationship to clinical features Journal of Rheumatology 17(3): 318-322
Freemont, A.J.; Jones, C.J. 1983: Endothelial specialization of salivary gland vessels for accelerated lymphocyte transfer in Sjögren's syndrome Journal of Rheumatology 10(5): 801-804
Lane, H.C.; Callihan, T.R.; Jaffe, E.S.; Fauci, A.S.; Moutsopoulos, H.M. 1983: Presence of intracytoplasmic IgG in the lymphocytic infiltrates of the minor salivary glands of patients with primary Sjögren's syndrome Clinical and Experimental Rheumatology 1(3): 237-239
Boumba, D.; Skopouli, F.N.; Moutsopoulos, H.M. 1995: Cytokine mRNA expression in the labial salivary gland tissues from patients with primary Sjögren's syndrome British Journal of Rheumatology 34(4): 326-333
Asashima, H.; Inokuma, S.; Onoda, M.; Oritsu, M. 2013: Cut-off levels of salivary beta2-microglobulin and sodium differentiating patients with Sjögren's syndrome from those without it and healthy controls Clinical and Experimental Rheumatology 31(5): 699-703
Li, X.-m.; Li, X.-p.; Qian, L.; Wang, G.-s.; Zhang, H.; Zhei, Z.-m.; Li, Q.; Chen, K.; Wang, X.-q.; Wang, Y.-p. 2007: Expression of CD4+ CD25+ regulatory T cells in peripheral blood and salivary gland of patients with primary Sjögren's syndrome Zhonghua Yi Xue Za Zhi 87(15): 1034-1036
Skopouli, F.N.; Li, L.; Boumba, D.; Stefanaki, S.; Hanel, K.; Moutsopoulos, H.M.; Krilis, S.A. 1998: Association of mast cells with fibrosis and fatty infiltration in the minor salivary glands of patients with Sjögren's syndrome Clinical and Experimental Rheumatology 16(1): 63-65