The all-solid-state benzydamine ion-selective electrode and dielectric-constant effect on the electrode linearity slope
Yao, S.Z.; Ma, W.L.; Zhu, A.X.; Nie, L.H.
Yao Xue Xue Bao 23(2): 130-136
1988
ISSN/ISBN: 0513-4870 PMID: 3188920 Document Number: 305688
All-solid-state benzydamine ion-selective electrode with ion-pair complex of benzydamine with hetero-tungstate as electroactive material showed good response performance, its lower limit of linearity response range is 1.5 .times. 10-6 mol/L with a slope of 58 mV/log C. The electrode can be used for potentiometric determination of benzydamine in blood and urine. Microgram and submicrogram amount of benzydamine can be determined using the proposed single-drop method. For electrodes based on ion-pair complex of benzydamine with hetero-poly acid, the response slope did not decrease significantly with decreasing dielectric constant in the ethanol.sbd.water mixed background. However, for electrode based on benzydamine dicyclohexylnaphthalene sulphonate, dipicrylaminate, tetraphenylborate, tetraiodobismuthate or picrate, the electrode linearity slope decreased continuously with decreasing dielectric constant.