High-dose etoposide therapy for extensive small cell lung cancer: a Cancer and Leukemia Group B Study
Luikart, S.D.; Propert, K.J.; Modeas, C.R.; Green, M.R.; Perry, M.C.
Cancer Treatment Reports 71(5): 533-534
1987
ISSN/ISBN: 0361-5960 PMID: 3032434 Document Number: 305381
Twenty-one previously untreated patients with extensive small cell lung cancer were treated with etoposide, 400 mg/m2/day for 3 consecutive days. Myelosuppression was severe, with a treatment-related death rate of 28%. Five partial responses were achieved. High-dose etoposide as given in this study produced unacceptable toxicity and no complete responses.
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