Adriamycin, cyclophosphamide and etoposide (ACE) in the treatment of small cell lung cancer
Ardizzoni, A.; Canobbio, L.; Pronzato, P.; Repetto, L.; Serrano, J.; Benvenuto, F.; Simonassi, C.; Baracco, F.; Faravelli, B.; Nosenzo, M.
Chemioterapia International Journal of the Mediterranean Society of ChemoTherapy 5(6): 416-419
1986
ISSN/ISBN: 0392-906X PMID: 3026668 Document Number: 279545
Thirty-five small cell lung cancer (SCLC) patients were treated with combination chemotherapy including adriamycin, cyclophosphamide, etoposide (ACE). Out of 32 evaluable patients there were 21.9% complete responses and 53.1% partial responses with an overall median survival of 37 weeks (50 weeks for patients with limited disease and 34 weeks for patients with extended disease). Toxicity was generally well tolerated. In conclusion the ACE regimen results in being active and safe in the treatment of SCLC.