Risk of hypoglycaemia with alternate-day growth hormone injections
Press, M.; Notarfrancesco, A.; Genel, M.
Lancet 1(8540): 1002-1004
1987
ISSN/ISBN: 0140-6736 PMID: 2883344 Document Number: 305365
Fasting hypoglycaemia developed in three growth hormone deficient children after the start of treatment with synthetic growth hormone. The effects, which occurred 36-670 h after each injection, may have been due to insulin-like effects of endogenous somatomedins after waning of insulin antagonism induced by growth hormone. Daily growth hormone injections may be necessary to maintain normal plasma glucose levels in young children.
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