Role of 131I-metaiodobenzylguanidine scintigraphy in the diagnosis of intestinal carcinoids
Bihl, H.; Sautter-Bihl, M.L.; Wilhelm, K.R.; Kimmig, B.
Nuklearmedizin. Nuclear Medicine 26(6): 263-267
1987
ISSN/ISBN: 0029-5566 PMID: 3438170 Document Number: 304980
Iodine-131 metaiodobenzylguanidine (131I-MIBG) is concentrated in a variety of neuroendocrine tumors, such as pheochromocytoma and neuroblastoma. Other neuroendocrine tumors from the APUD-cell system such as carcinoid tumors, may possess this uptake capability as well. We investigated 11 patients suffering from intestinal carcinoid with 131I-MIBG in order to determine the value of MIBG scintigraphy in these tumors. MIBG scans were positive in 5 out of 11 patients (45%). False-positive MIBG-scans did not occur. No correlation between MIBG uptake, clinical symptoms and urinary 5-HIAA level could be found.