Ultrastructure of brain tumor
Luo, S.Q.; Zhang, Y.X.
Zhonghua Zhong Liu Za Zhi 9(2): 115-117
1987
ISSN/ISBN: 0253-3766 PMID: 2820679 Document Number: 304882
Ultrastructure of 15 brain tumors (6 astrocytomas, 5 meningiomas, 2 medulloblastomas and 2 Schwannomas) was observed by transmission electron microscope. In astrocytoma, both the fibrous and protoplasmic astrocytes were found. There were abundant capillaries among the tumor cells. The glia limitans outside the base membrane of certain capillaries were destroyed to different degrees. It indicates that the blood brain barrier may be damaged. Ultrastructurally, medulloblastoma cells may be divided into types I and II. The former was poorly differentiated but the latter was differentiated differently. Meningioma was similar to Schwannoma with complex cell membrane projections. The former had a lot of round mitochondria and filaments in the projections, between which desmosomes were observed. Schwannoma had the typical collagenous fibers among the projections. As to the epithelioid ultrastructure of meningioma, the authors speculate that the majority of meningiomas originate from the mesothelial cells of the arachnoid granulations.