Electrophysiologic observation of the effects of Matrine Co against arrhythmia induced by Chinese cobra venom on isolated rat sinus node and papillary muscles
Wang, Y.L.; Ba, Y.K.
Journal of Traditional Chinese Medicine 7(1): 35-40
1987
ISSN/ISBN: 0255-2922 PMID: 3613639 Document Number: 304511
The present study was to observe the effect of Matrine Co against arrhythmia induced by Chinese cobra venom (1 .times. 1-6gm/ml) on isolated rat sinus node and papillary muscle preparations. Results showed that a single dose 4 .times. 10-4gm/ml or 3 repeated doses of Matrine Co could counter arrhythmia after being given within 3 min. The reversion rate was 90.4-100%.
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