Pituitary growth hormone from human cadavers: neurologic disease in ten recipients
Rappaport, E.B.; Graham, D.J.
Neurology 37(7): 1211-1213
1987
ISSN/ISBN: 0028-3878 PMID: 3474545 Document Number: 304450
Creutzfeldt-Jakob disease (CJD) has been reported in three US patients previously treated with human growth hormone derived from large pools of human cadaver pituitary glands (pit-hGH). Neurologic disorders other than CJD occurred in 10 growth hormone-deficient patients treated with pit-hGH. These 10 cases could have been chance events or true syndromes; some cases may have been caused by transmissible agents contained in the pooled growth hormone product.
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