Histological examination of combined effects of chemotherapeutical agents and differently fractionated irradiations in transplanted solid Ehrlich carcinoma of mice. III. Observations after vincristine treatment
Unger, E.
Strahlentherapie und Onkologie Organ der Deutschen Rontgengesellschaft . 163(12): 803-806
1987
ISSN/ISBN: 0179-7158 PMID: 3424081 Document Number: 304449
Vincristine treatment alone does not evoke estimable histological damage in solid Ehrlich carcinoma. However, when combined with fractionated local X-irradiation it causes more severe damage than the irradiation alone, consequently vincristine has a synergistic effect in radiation therapy. Comparing the effects of irradiation of the same total dose fractionated differently and combined with vincristine, one cannot find any characteristic and consequent histological differences.