Pathologic features of picornavirus infections in cats
Holzinger, E.A.; Kahn, D.E.
American Journal of Veterinary Research 31(9): 1623-1630
1970
ISSN/ISBN: 0002-9645 PMID: 4918900 Document Number: 30424
Cats inoculated intranasally with an aerosol of picornavirus developed a clinically recognizable disease entity. In addition to mild rhinitis and conjunctivitis, eight of the 46 cats had palatine or glossal ulcerations (or both). Viral antigen was seen by fluorescent antibody techniques at the margins of the ulcers. The significant lesions were broncho-pneumonia, which occurred early in the disease, and proliferation of alveolar and bronchiolar epithelium in an "adenomatoid" manner, which occurred later. Viral antigen in reactive cells in the lung was demonstrated by fluorescent antibody techniques. Nine of the 46 cats had transverse dark bands on the spleen, not previously reported.