Amygdaloid kindling in the rat after a lesion of the locus coeruleus induced by 6-hydroxydopamine
N'Gouemo, P.; Watanabe, K.; Rondouin, G.; Sandillon, F.; Privat, A.; Baldy-Moulinier, M.
Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 181(1): 22-29
1987
ISSN/ISBN: 0037-9026 PMID: 2954618 Document Number: 303492
Amygdaloid kindling was studied after locus coeruleus lesion with 6-hydroxydopamine in the rat. Specific lesions, controlled with immunocytochemistry using an anti-norepinephrine antibody, facilitated the amygdaloid kindling. These results indicate that the noradrenergic system plays an inhibitory role in the development of amygdaloid kindling.