Relationship between the serum levels of calcitonin, calcium, phosphorus and red blood cell Ca-ATPase during calcium infusion to healthy volunteers
Shainkin-Kestenbaum, R.; Zimlichman, S.; Liel, Y.
Mineral and Electrolyte Metabolism 13(2): 69-71
1987
ISSN/ISBN: 0378-0392 PMID: 2826978 Document Number: 302571
The relationship between the serum levels of calcitonin (CT), Ca and P, and red blood cell Ca-ATPase (RBC Ca-ATPase) was investigated during Ca infusion given to 6 healthy volunteers. The following results were obtained: Ca infusion, during a 3-hour period, raised serum levels of CT, P and RBC Ca-ATPase with significant correlations between serum CT and RBC Ca-ATPase. The increase in RBC Ca-ATPase activity was accompanied by an appropriate decrease in K-Na-ATPase activity. This study supports the in vitro observations concerning the regulation of intracellular Ca level by CT. Activation of Ca-ATPase during Ca loading is important for red cell survival.