Autologous anticancer antigen preparation for specific immunotherapy in advanced renal cell carcinoma
Kurth, K.H.; Marquet, R.; Zwartendijk, J.; Warnaar, S.O.
European Urology 13(1-2): 103-109
1987
ISSN/ISBN: 0302-2838 PMID: 3582439 Document Number: 302233
33 patients with metastatic renal cell carcinoma were treated intradermally with an autologous (29 patients) or allogeneic (4 patients) irradiated tumor cell preparation mixed with Corynebacterium parvum given monthly after palliative nephrectomy (27 patients) or excision of tumor metastases (2 patients). No significant toxicity was produced. 8 patients (24%) underwent objective responses. Responding patients had a median survival of 32 months, the median survival of all patients was 17 months (differences not significant).