Stabilization of pressure drop in the feeder arteries of rats as affected by an increase in blood flow

Nikol'skiĭ, V.P.; Rogoza, A.N.; Khaiutin, V.M.

Biulleten' Eksperimental'noi Biologii i Meditsiny 104(9): 259-261

1987


ISSN/ISBN: 0365-9615
PMID: 3663900
Document Number: 301628
The dependence of the pressure drop (PD) along conducting vessels between the aorta and the distal end of a. saphena on the blood flow in the artery has been studied in rats. The PD was shown to react to rapid blood flow increase from 0.6 to 1.2 ml/min, with a drastic upstroke followed by a gradual decrease to the initial value within 20 s. When the blood flow was returned to the initial level the PD was recovered during 40 s. A rapid flow increase from 0.1 to 1.0 ml/min in 3 s was accompanied by proportional changes in PD. However, a slow blood flow increase from 0.1 to 1.5 ml/min in 600 s did not induce any marked changes in PD in the range of the blood flow from 0.5 to 1.5 ml/min. The observed stabilization of PD may be attributed to the property of conducting arteries to increase their internal diameter in response to blood flow increase.

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