Hemophagocytic syndrome in Dengue hemorrhagic fever with severe multiorgan complications

Srichaikul, T.; Punyagupta, S.; Kanchanapoom, T.; Chanokovat, C.; Likittanasombat, K.; Leelasiri, A.

Journal of the Medical Association of Thailand 91(1): 104-109

2008


ISSN/ISBN: 0125-2208
PMID: 18386553
Document Number: 3015
A 46 year old woman who presented with severe multiorgans involvement including liver brain, cardio-pulmonary failure, gastrointestinal bleeding, progressive cytopenia, DIC and hemophagocytic syndrome during the convalescent phase of Dengue type II has been successfully treated primarily with pulse methyl prednisolone and high dose intravenous immunoglobulin G. The authors believe that HPCS are not infrequently seen with high mortality and recommended early diagnosis and treatment with the regimen. This is the first complete report of hemophagocytic syndrome in adult dengue hemorrhagic fever in Thailand. The literature of HPCS in DHF was reviewed and discussed.

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Hemophagocytic syndrome in Dengue hemorrhagic fever with severe multiorgan complications