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Changes in the pharmacodynamic properties of promedol, droperidol and dimedrol in burn shock and combined radiation-thermal injury

Il'iuchenok, T.Iu.; Matveeva, I.A.; Budagov, R.O.

Farmakologiia i Toksikologiia 50(1): 71-74

1987

ISSN/ISBN: 0014-8318
PMID: 3556555
Document Number: 301327
Toxic and pharmacological properties of promedol, droperidol and dimedrol were studied during burn shock and combined radiation and thermal injury (CRTI). Acute toxicity and analgesic effect of promedol were shown to increase in the given period Droperidol analgesic effect enhanced in burn and CRTI, cataleptic action enhanced only in CRTI. A decrease of antihistaminic activity of dimedrol was more pronounced in CRTI.

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