Occurrence of aminopropylhomospermidine and canavalmine in the hamster epididymis

Matsuzaki, S.; Xiao, L.P.; Suzuki, M.; Hamana, K.; Niitsu, M.; Samejima, K.

Biochemistry International 15(4): 817-822

1987


ISSN/ISBN: 0158-5231
PMID: 3435545
Document Number: 301209
The Syrian hamster epididymis contains rather high levels of sym-homospermidine, N1-acetylspermidine and N1-acetylspermine in addition to the common polyamines putrescine, spermidine, and spermine. In the present study two other polyamines were identified in adult hamster epididymis by gas chromatography; they are aminopropylhomospermidine [NH2 (CH2)3NH(CH2)4 NH (CH2)4NH2] and canavalmine [NH2 (CH2)4NH(CH2)3NH(CH2)4NH2]. The molar ratio of the former to the latter was about 2:1. This is the first report to show that tetraamines other than spermine are present in mammalian tissues.

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