Sympatho-inhibitory mechanisms acting at sympathetic ganglia to attenuate hypothalamic-induced pressor effect in the cat
Blum, B.; Israeli, J.; Hart, O.; Mihiz, M.; Farchi, M.
Experientia 43(10): 1106-1109
1987
ISSN/ISBN: 0014-4754 PMID: 2889613 Document Number: 298566
Pressor and tachycardic effects induced in the cat by stimulation of a lateral hypothalamic (LH) site, are shown to be mediated by sympathetic ganglia nicotinic receptor, and potentiated under atropine methyl nitrate sympathetic ganglia blockage. It is postulated that a sympatho-inhibitory pathway muscarinic ganglionic mechanism, co-activated by the LH stimulation, attenuates the pressor and tachycardiac effects, the potentiation presumably being a manifestation of blockage of that mechanism.