Immunoblot analysis of Salmonella typhi lipopolysaccharide (LPS) using typhoid sera
Vullo, V.; Mastroianni, C.M.; Contini, C.; Cignarella, L.; Massetti, A.P.; Falciano, M.; Paoletti, F.; Di Seri, M.
Bollettino dell'Istituto Sieroterapico Milanese 66(2): 130-133
1987
ISSN/ISBN: 0021-2547 PMID: 2444235 Document Number: 298391
Lipopolysaccharide (LPS) of Salmonella typhi has been analyzed by immunoblotting with pooled sera from typhoid patients. Pooled typhoid sera have recognized all the antigenic determinants of S. typhi LPS, giving a strong reaction with the repeating units on the O-side chains as well as with the core region. Cross-reacting antigens have been observed with the LPS of S. typhimurium and S. enteritidis, while no heterologous reactions were seen with the LPS of Escherichia coli strains.