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Production of cytotoxic factor for oligodendrocytes by stimulated astrocytes

Robbins, D.S.; Shirazi, Y.; Drysdale, B.E.; Lieberman, A.; Shin, H.S.; Shin, M.L.

Journal of Immunology 139(8): 2593-2597

1987

ISSN/ISBN: 0022-1767
PMID: 3116087
Document Number: 297488
Stimulation of rat astrocytes in vitro by calcium ionophore A23187 and/or lipopolysaccharide results in the generation of a cytotoxic factor that is functionally similar to the previously described macrophage-derived cytotoxic factor, tumor necrosis factor. Like the macrophage product, the astrocyte cytotoxic factor kills murine L 929 cells targets. In addition, it kills rat oligodendrocytes, the myelin-producing cells of the central nervous system. Human recombinant tumor necrosis factor also has cytotoxic activity directed against rat oligodendrocytes.

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Vacheron, F.; Guenounou, M.; Zinbi, H.; Nauciel, C. 1986: Release of a cytotoxic factor by macrophages stimulated with adjuvant-active peptidoglycans Journal of the National Cancer Institute 77(2): 549-553
Fujii, Y.; Inoue, T.; Ito, M.; Kimura, S.; Fuyama, S.; Arai, S.; Naiki, M.; Sendo, F. 1986: Heterogeneous profiles of a factor that renders neutrophils cytotoxic obtained from a concanavalin A-stimulated spleen cell culture in partial purification process Journal of Immunology 136(10): 3693-3699
Yamamoto, A.; Nagamuta, M.; Usami, H.; Sugawara, Y.; Watanabe, N.; Niitsu, Y.; Urushizaki, I. 1986: Production of a cytotoxic factor in mouse peritoneal fluid by OK-432, a streptococcal preparation Gan to Kagaku Ryoho. Cancer and ChemoTherapy 13(5): 1905-1910
Moxley, G.; Stern, A.G.; Carlson, P.; Estrada, E.; Han, J.; Benson, L.L. 2004: Premenopausal sexual dimorphism in lipopolysaccharide-stimulated production and secretion of tumor necrosis factor Journal of Rheumatology 31(4): 686-694
Elias, J.A.; Lentz, V.; Cummings, P.J. 1991: Transforming growth factor-beta regulation of IL-6 production by unstimulated and IL-1-stimulated human fibroblasts Journal of Immunology 146(10): 3437-3443
Yoshinaga, T.; Nomura, H.; Nishimura, H.; Tomino, S.; Kawakita, M.; Takatsuki, K.; Fujimoto, K.; Etou, Y.; Nakaji, T.; Kiyama, T. 1986: Production of a cytotoxic factor into malignant pleural fluid by OK-423, a streptococcal preparation--kinetic analysis Gan to Kagaku Ryoho. Cancer and ChemoTherapy 13(8): 2675-2677
Jennings, G.R.; Castresana, M.R.; Newman, W.H. 2004: Regulation of tumor necrosis factor-alpha production in the isolated rat heart stimulated by bacterial lipopolysaccharide or reactive oxygen American Surgeon 70(9): 797-800
Jirillo, E.; Monno, R.; Munno, I.; De Santis, A.; Fumarola, D. 1977: Effects of tilorone hydrochloride on cellular immunity (leukocyte inhibiting factor production from human lymphocyte stimulated by E. coli lipopolysaccharide) Bollettino dell'Istituto Sieroterapico Milanese 56(4): 299-302
Le, J.M.; Vilcek, J. 1987: Accessory function of human fibroblasts in mitogen-stimulated interferon-gamma production by T lymphocytes. Inhibition by interleukin 1 and tumor necrosis factor Journal of Immunology 139(10): 3330-3337
Malipiero, U.V.; Frei, K.; Fontana, A. 1990: Production of hemopoietic colony-stimulating factors by astrocytes Journal of Immunology 144(10): 3816-3821
Yoshimoto, T.; Nagai, N.; Ohkusu, K.; Ueda, H.; Okamura, H.; Nakanishi, K. 1998: LPS-stimulated SJL macrophages produce IL-12 and IL-18 that inhibit IgE production in vitro by induction of IFN-gamma production from CD3intIL-2R beta+ T cells Journal of Immunology 161(3): 1483-1492
Richards, A.L.; Okuno, T.; Takagaki, Y.; Djeu, J.Y. 1988: Natural cytotoxic cell-specific cytotoxic factor produced by IL-3-dependent basophilic/mast cells. Relationship to TNF Journal of Immunology 141(9): 3061-3066
Kendall, L.; Sabbadini, E. 1981: Effect of Bacillus Calmette-Guérin on the in vitro generation of cytotoxic T lymphocytes. I. Effect of BCG on the frequency of cytotoxic T lymphocyte precursors and on the production of helper factors Journal of Immunology 127(1): 234-238
Tóth, Z.; Séress, L.; Tóth, P.; Ribak, C.E.; Gallyas, F. 1997: A common morphological response of astrocytes to various injuries: "dark" astrocytes. a light and electron microscopic analysis Journal für Hirnforschung 38(2): 173-186
Rafałowska, J.; Podlecka, A. 1998: Does the pathological factor in amyotrophic lateral sclerosis (ALS) damage also astrocytes? Folia Neuropathologica 36(2): 87-93
Pomerance, M.; Gavaret, J.M.; Breton, M.; Pierre, M. 1994: Growth factor-regulated phosphatidylinositol-3-kinase in astrocytes. Involvement of pp60c-src Cellular and Molecular Biology 40(5): 653-664
Valone, F.H.; Epstein, L.B. 1988: Biphasic platelet-activating factor synthesis by human monocytes stimulated with IL-1-beta, tumor necrosis factor, or IFN-gamma Journal of Immunology 141(11): 3945-3950
Tursi, A.; Trizio, D.; Ferrannini, A. 1971: Antilymphocyte serum. Effects on blastogenesis and cytotoxic activity of lymphocytes stimulated with phytohemagglutinins Folia Allergologica 18(2): 191-194
Selmaj, K.W.; Farooq, M.; Norton, W.T.; Raine, C.S.; Brosnan, C.F. 1990: Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor Journal of Immunology 144(1): 129-135
Russell, J.H. 1986: Phorbol-ester stimulated lysis of weak and nonspecific target cells by cytotoxic T lymphocytes Journal of Immunology 136(1): 23-27