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Pneumocystis carinii pneumonia in infants given adrenocorticotropic hormone for infantile spasms

Quittell, L.M.; Fisher, M.; Foley, C.M.

Journal of Pediatrics 110(6): 901-903

1987

ISSN/ISBN: 0022-3476
PMID: 3035157
Document Number: 296197
The case histories are reported of 3 infants in whom P. carinii pneumonia developed following ACTH treatment for infantile spasms. In all, 23 children had received ACTH treatment for spasms over a period of 5 years at the St. Christopher's Hospital in Philadelphia, USA. The 3 had been given ACTH daily for at least 4 months without achieving seizure control. Other causes of immune suppression or risk factors for AIDS were absent.

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