Changing pattern of drug use in relation to disease duration of rheumatoid arthritis

van Saase, J.; Vandenbroucke, J.; Valkenburg, H.; Boersma, J.; Cats, A.; Festen, J.; Hartman, A.; Huber-Bruning, O.; Rasker, J.; Weber, J.; van Saase, J; Vandenbroucke, J; Valkenburg, H; Boersma, J; Cats, A; Festen, J; Hartman, A; Huber-Bruning, O; Rasker, J; Weber, J

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Changing pattern of drug use in relation to disease duration of rheumatoid arthritis

van Saase, J.; Vandenbroucke, J.; Valkenburg, H.; Boersma, J.; Cats, A.; Festen, J.; Hartman, A.; Huber-Bruning, O.; Rasker, J.; Weber, J.

Journal of Rheumatology 14(3): 476-478

1987

ISSN/ISBN: 0315-162X

PMID: 3625629

Document Number: 295268

The prevalent use of antirheumatic drugs in a cohort of 311 middle aged female patients with seropositive and seronegative rheumatoid arthritis (RA) was investigated. Seropositive patients used a greater amount and more aggressive drugs during each decade of disease duration. The overall use of drugs decreased with disease duration, except for a subgroup of seropositive patients with RA who, with increased disease duration, used more aggressive drugs.