Comparison of the effectiveness of acyclovir and vidarabine in superficial herpes keratitis
Genée, E.; Maith, J.
Klinische Monatsblatter für Augenheilkunde 191(1): 30-32
1987
ISSN/ISBN: 0023-2165 PMID: 3309444 Document Number: 294947
In a double-blind clinical trial 28 patients with primary and recurrent herpetic corneal ulcerations were treated either with 3% Acyclovir eye ointment or 3% Adenosine Arabinoside eye ointment. In 11 out of 14 (78%) patients treated with Acyclovir and 8 out of 14 (57%) patients treated with Adenosine Arabinoside the ulcerations healed within a treatment period of 6.5 days and 8 days respectively (no statistical significance). However, the results revealed that Acyclovir was more effective. Both drugs were well tolerated.