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The relevance of hyperresponsiveness but not of atopy to FEV1 decline. Preliminary results in a working population

Annesi, I.; Neukirch, F.; Orvoen-Frija, E.; Oryszczyn, M.P.; Korobaeff, M.; Doré, M.F.; Kauffmann, F.

Bulletin Europeen de Physiopathologie Respiratoire 23(4): 397-400

1987

ISSN/ISBN: 0395-3890
PMID: 3318969
Document Number: 294682
Five-year FEV1 decline in 329 working men was shown to be significantly related only among eversmokers to methacholine bronchial hyperresponsiveness (assessed at the end of follow-up), allergic rhinitis and rhinitis induced by cold air, independent of asthma and FEV1 level. Positive skin prick test was not associated with FEV1 decline.

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