Inhibitory action of flurbiprofen and mopidamole on tumor lung metastasis formation in mice
Mamytbeková, A.; Rezábek, K.; Grimová, J.; Svobodová, J.
Cancer Treatment Reports 71(11): 1089-1090
1987
ISSN/ISBN: 0361-5960 PMID: 3677114 Document Number: 293586
Flurbiprofen, 0.25 mg/kg, administered to mice orally once daily during 3 days prior to an iv transplantation of Lewis lung carcinoma cells, protected 50%-57% of experimental animals from the formation of lung tumor colonies. With the daily dose of 1.0 mg/kg, this effect was less pronounced. Mopidamole, twice daily 90 mg/kg orally during 3 days, did not have this effect.
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