Maternal and neonatal responses to alfentanil administered before induction of general anaesthesia for caesarean section
Dann, W.L.; Hutchinson, A.; Cartwright, D.P.
British Journal of Anaesthesia 59(11): 1392-1396
1987
ISSN/ISBN: 0007-0912 PMID: 3120764 Document Number: 292892
The cardiovascular response to tracheal intubation was compared in two groups of patients undergoing elective Caesarean section. Both groups received a standard technique of general anaesthesia. One of the groups received alfentanil 10 .mu.g kg-1 1 min before induction of anaesthesia, the other acted as a control group. In the alfentanil group there was a significant modification of the cardiovascular response to intubation as compared with the control group (P < 0.01). No adverse effect on the neonate was seen. However, a significant increase in the incidence of postoperative nausea occurred in mothers in the alfentanil group (P < 0.05).